Banca de QUALIFICAÇÃO: ISAIAS LOPES

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : ISAIAS LOPES
DATE: 12/02/2025
TIME: 08:30
LOCAL: BLOCO DA PÓS GRADUAÇÃO
TITLE:

PAIN PHENOTYPE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: A

CROSS-SECTIONAL STUDY

KEY WORDS:

 Lupus Erythematosus, Systemic; Chronic Pain; Central Nervous System
Sensitization.

PAGES: 46
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Introduction: Systemic Lupus Erythematosus (SLE) is an autoimmune disease that promotes
chronic systemic inflammation caused by production of autoantibodies and deposition of
immune complexes into different organs and structures, with a period of activation and
remission. Objective: To identify the phenotype of chronic pain in patients with SLE in
different regions of Brazil. Material and methods: This observational cross-sectional study
will have as inclusion criteria: individuals aged over 18 years of both genders diagnosed with
SLE; presence of pain for at least 3 months; and as exclusion criteria: individuals with another
type of lupus (cutaneous or induced by medication); people without pain in the last 3 months.
Results: The study sample consisted of 64 individuals diagnosed with Systemic Lupus
Erythematosus, from the North, Northeast, Southeast, and South regions of Brazil, with the
highest number of participants from the Northeast and Southeast regions. Most participants
were single, of mixed ethnicity, and had completed high school. Clinically, the average pain
intensity was moderate, and the majority of participants used, on average, three medications.
Initial Considerations: The chronic pain phenotype in SLE patients in Brazil is multifactorial,
and is related to a central sensitization process, in addition to psychosocial factors such as
fatigue and anxiety, and neuropathic components.
Keywords: Lupus Erythematosus, Systemic; Chronic Pain; Central Nervous System
Sensitization.

COMMITTEE MEMBERS:
Interno - 3283051 - DIEGO BULCAO VISCO
Presidente - 3066678 - NATALIA CAMARGO RODRIGUES IOSIMUTA
Interno - 2389271 - WOLLNER MATERKO