Banca de DEFESA: LUCAS DOS SANTOS NUNES

Uma banca de DEFESA de MESTRADO foi cadastrada pelo programa.
STUDENT : LUCAS DOS SANTOS NUNES
DATE: 22/05/2025
TIME: 15:00
LOCAL: https://meet.google.com/gxc-ymwn-omr
TITLE:

TYPE 2 DIABETES AND QUALITY OF LIFE: AN ANALYSIS OF
PSYCHOEMOTIONAL AND BIOCHEMICAL ASPECTS

KEY WORDS:

Keywords: Glycemic Control; Psychological Stress; Quality of Life.

PAGES: 69
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Type 2 Diabetes Mellitus (T2DM) is a chronic condition with high global prevalence, exerting
a significant impact on both public health and economic systems. It is characterized by a
metabolic dysfunction resulting from insufficient insulin secretion and/or peripheral
resistance to insulin action. Lifestyle-related factors, such as inadequate diet, physical
inactivity, and, more broadly, stress, have been associated with the development and
worsening of T2DM. The dysfunctional interaction between these factors contributes to
physiological alterations and negatively affects the quality of life of affected individuals. In
light of this, the aim of this study was to analyze the psycho-emotional aspects and their
relationship with biochemical indicators in the quality of life of individuals with type 2
diabetes (T2DM) receiving care at a Primary Health Care Unit. Participants included
individuals with a previous diagnosis of T2DM who received care at the Primary Health Unit
of the Federal University of Amapá. This is a descriptive study with a quantitative approach,
in which stress levels and quality of life were assessed using the Depression, Anxiety and
Stress Scale – 21 Items (DASS-21), the Diabetes-39 Quality of Life Questionnaire (D-39),
and the Diabetes Distress Scale (DDS-17). Biochemical parameters, including glycated
hemoglobin (HbA1c), fasting blood glucose, triglycerides, and cortisol, were also measured.
The majority of participants were female, over 60 years of age, retired, exclusively dependent
on the public health system (SUS), and presented systemic arterial hypertension as the most
frequent comorbidity. Regarding the DASS-21 results, most participants showed normal
levels of depression, anxiety, and stress. However, the D-39 scores revealed a significant
impact of T2DM on quality of life, particularly in the domains of diabetes control and
anxiety/concern about health status. The DDS-17 indicated higher levels of distress in the
domains of emotional burden and dietary regimen. As for the biochemical parameters, cortisol
levels were within normal ranges, while mean values of fasting glucose (186 mg/dL), HbA1c
(8.41%), and triglycerides (169 mg/dL) were elevated compared to reference values. Overall,
the findings reveal biochemical alterations compatible with poor glycemic control, alongside
indicators of emotional distress and impaired quality of life, reinforcing the importance of
comprehensive and interdisciplinary approaches in the clinical management of T2DM.
Keywords: Glycemic Control; Psychological Stress; Quality of Life.

COMMITTEE MEMBERS:
Interna - 3299691 - LETHICIA BARRETO BRANDÃO
Presidente - 1432793 - MARIA IZABEL CORTES VOLPE
Externa ao Programa - 1453748 - MARIA VIRGINIA FILGUEIRAS DE ASSIS MELLO - nullInterna - 1015007 - MARLUCILENA PINHEIRO DA SILVA