Banca de QUALIFICAÇÃO: LUCAS DOS SANTOS NUNES

Uma banca de QUALIFICAÇÃO de MESTRADO foi cadastrada pelo programa.
STUDENT : LUCAS DOS SANTOS NUNES
DATE: 28/04/2025
TIME: 15:00
LOCAL: https://meet.google.com/ywb-qdbr-qqm
TITLE:

TYPE 2 DIABETES AND QUALITY OF LIFE: AN ANALYSIS OF
PSYCHOEMOTIONAL AND BIOCHEMICAL ASPECTS

KEY WORDS:

Keywords: Glycemic Control; Psychological Stress; Quality of Life.

PAGES: 69
BIG AREA: Ciências da Saúde
AREA: Saúde Coletiva
SUMMARY:

Type 2 Diabetes Mellitus (T2DM) is a chronic condition with high global prevalence, exerting a
significant impact on both public health and economic systems. It is characterized by a
metabolic dysfunction resulting from insufficient insulin secretion and/or peripheral resistance
to insulin action. Lifestyle-related factors, such as inadequate diet, physical inactivity, and,
more broadly, stress, have been associated with the development and worsening of T2DM.
The dysfunctional interaction between these factors contributes to physiological alterations
and negatively affects the quality of life of affected individuals. In light of this, the aim of this
study was to analyze the psycho-emotional aspects and their relationship with biochemical
indicators in the quality of life of individuals with type 2 diabetes (T2DM) receiving care at a
Primary Health Care Unit. Participants included individuals with a previous diagnosis of T2DM
who received care at the Primary Health Unit of the Federal University of Amapá. This is a
descriptive study with a quantitative approach, in which stress levels and quality of life were
assessed using the Depression, Anxiety and Stress Scale – 21 Items (DASS-21), the Diabetes-39
Quality of Life Questionnaire (D-39), and the Diabetes Distress Scale (DDS-17). Biochemical
parameters, including glycated hemoglobin (HbA1c), fasting blood glucose, triglycerides, and
cortisol, were also measured. The majority of participants were female, over 60 years of age,
retired, exclusively dependent on the public health system (SUS), and presented systemic
arterial hypertension as the most frequent comorbidity. Regarding the DASS-21 results, most
participants showed normal levels of depression, anxiety, and stress. However, the D-39 scores
revealed a significant impact of T2DM on quality of life, particularly in the domains of diabetes
control and anxiety/concern about health status. The DDS-17 indicated higher levels of distress
in the domains of emotional burden and dietary regimen. As for the biochemical parameters,
cortisol levels were within normal ranges, while mean values of fasting glucose (186 mg/dL),
HbA1c (8.41%), and triglycerides (169 mg/dL) were elevated compared to reference values.
Overall, the findings reveal biochemical alterations compatible with poor glycemic control,
alongside indicators of emotional distress and impaired quality of life, reinforcing the
importance of comprehensive and interdisciplinary approaches in the clinical management of
T2DM.

COMMITTEE MEMBERS:
Interna - 1730962 - ANNELI MERCEDES CELIS DE CARDENAS
Presidente - 1432793 - MARIA IZABEL CORTES VOLPE
Externa ao Programa - 1453748 - MARIA VIRGINIA FILGUEIRAS DE ASSIS MELLO - null