SOCIODEMOGRAPHIC AND CLINICAL PROFILE OF PATIENTS WITH SYSTEMIC LUPUS
ERYTHEMATOSUS
Keywords: Systemic Lupus Erythematosus; Epidemiological Profile; Quality of Life; Depression.
Introduction: Systemic Lupus Erythematosus (SLE) is a chronic, autoimmune, and
multisystemic disease. With a low incidence, it presents various manifestations that
complicate diagnosis and impair the quality of life of affected individuals. Investigating a
sociodemographic and clinical profile is essential to understanding the characteristics of the
vulnerable population, identifying patterns of disease manifestation and progression, and
exploring associated environmental factors. Objectives: To identify the sociodemographic and
clinical profile of patients with Systemic Lupus Erythematosus. The specific objectives of the
study include analyzing clinical patterns and predominant manifestations in the population and
investigating regional inequalities. Methodology: This is a descriptive observational study with
a cross-sectional design. Data were collected through interviews conducted at the Physical
Therapy Department of the Federal University of Amapá. Participants included individuals over
18 years old with a diagnosis of Systemic Lupus Erythematosus. Data collection was performed
using a semi structured questionnaire covering personal, sociodemographic and clinical
information.
Results: The sample consisted predominantly of brown-skinned women (60.6%), single
(47.5%), and with complete high school or higher education (87.9%). The mean age was 39.3
years, and the mean time since diagnosis was up to 5 years for most participants (36.1%). A
high prevalence of depressive symptoms was observed (70.8%), with emphasis on mild and
moderate depression (25.3% each). Pain was reported by 68.75% of participants, with
significant impacts on sleep, mood, and daily activities. The SF-36 analysis revealed widespread
impairment in quality of life, particularly in dimensions related to physical limitations, pain,
and general health status. The main comorbidities associated with SLE were hypertension
(36.36%), rheumatic diseases (37%), and varicose veins (26.26%). Conclusion: This study
contributes to understanding the regional specificities of SLE in the Amazonian context highlighting the need for public policies aimed at improving diagnosis, treatment, andcomprehensive care for this population. The findings reinforce the importance of
multidisciplinary and personalized approaches for SLE patients. Future research is essential to
expand knowledge about disease and support effective interventions.