.

Suicide constitutes a serious public health problem and is the second leading cause of mortality
among the population aged 10 to 29 in the State of Amapá. The general objective of this study
was to characterize the care pathway for individuals with suicidal behavior in the State of
Amapá. The specific objectives were to identify the epidemiological profile of individuals
exhibiting suicidal behavior in the state, describe the profile of healthcare professionals
attending to these individuals, and depict the network of care for suicidal behavior. This
descriptive, observational, retrospective, cross-sectional study utilized secondary data from the
National System of Notifiable Diseases (SINAN) and primary data obtained through
questionnaires. The results highlighted a growing trend in suicide attempts among young
females and adolescents, a high pattern of repetition, and significant underreporting. Individuals
with suicidal behavior access the healthcare network belatedly, primarily through emergency
services. Professionals perceived themselves as prepared to assist individuals in crisis due to
suicidal behavior, despite having low exposure to the topic. Difficulties were identified in
communication and coordination among network services, a lack of protocols and care flows,
and gaps in assistance, creating barriers to ongoing care. It is inferred, therefore, that the care
pathway requires structuring processes, implementation of a care line, expansion of specialized
mental health care, enabling matrix support for primary care teams, in addition to investment
in continuous education to qualify network professionals and enhance and improve
epidemiological information.

Introduction: Systemic Arterial Hypertension and Diabetes Mellitus are chronic
conditions that require longitudinal follow-up and care for management and control.
Considering that these conditions are treated and followed up in primary health care,
it is almost always the nurse who welcomes them and carries out the initial
consultation. From this perspective, the main working instrument of this professional is
the Nursing Consultation (NC). Therefore, it is important to use technology, such as an
assistive device in the nursing consultation, in order to direct care to the person being
consulted. Objective: To build and validate health care technology, in the format of a
form for nursing consultations in primary health care for people with Systemic Arterial
Hypertension and/or Diabetes Mellitus, supported by the Theory of Diversity and
Universality of Cultural Care, by Madeleine Leininger. Material and Methods:
Exploratory methodological research developed in three stages: integrative literature
review, construction and content validation. The construction of the technology was
based on an integrative review, and validation was carried out by a committee of
experts and target audience, composed of nurses who care for chronic conditions in
primary health care or have expertise in the area. The committees responded to two
stages to validate the technology, namely, the first to validate the domains, and the
second to validate the items in each domain, for which the Agreement Rate and
Content Validity Index (CVI) were used, both with a cutoff point for validation at 80%
(0.8). Data collection took place from December 2023 to July 2024, using a
questionnaire sent via Google Forms to the committees; a round table discussion was
added for the target audience. The analysis and interpretation of the data was carried
out through the statistical treatment of the data using absolute and relative frequencies
to characterize the responses of the participants, the Binomial Test, to verify
agreement for content validation, with a significance level of five percent (5%), the
Kappa Index, to measure the level of agreement and consistency of the committees in
relation to the permanence or otherwise of the items in the technology and Cronbach's
alpha coefficient (α) to analyze internal reliability. Results: 11 experts, 35 people from
the target audience participated in the Technology Content validation, with an
agreement rate of 88.81% and 96.5% respectively; Content Validity Index of 0.91 and
0.92, respectively; Kappa index > 0.61 and Cronbach's alpha coefficient (α) 0.772 and
0.922 respectively. The contributions of the committees were partially, completely or
not accepted by the author. Conclusion: The assistive technology called "Nursing
Consultation for people with Hypertension and/or Diabetes based on Congruent Care"
was validated in the first round of evaluation by both committees, indicating that it is
reliable for use in the Nursing Consultation in primary care.

Introduction: Aging is a natural process consisting of physiological changes that can
compromise the mobility and autonomy of older adults. The decrease in visual acuity affects
the ability to detect obstacles and maintain balance, impacting independence and quality of life.
Objective: To assess vision-related quality of life and its influence on falls in a group of elderly
individuals in the municipality of Santana-AP. Materials and Methods: This is a descriptive,
cross-sectional, and quantitative study, involving the participation of 57 elderly individuals
from the Happy Life group. The Snellen Chart and the National Eye Institute Visual Function
Questionnaire (NEI VFQ-25) were used to assess visual acuity and aspects of vision-related
quality of life. The significance level adopted for the analyses was p-value <0.05. Data from
the collection instruments were analyzed using Jamovi software through the Spearman test.
Results: There was a statistically significant association between vision-related quality of life
and falls, as indicated by the Spearman test applied to the NEI VFQ-25 questionnaire data with
a p-value of 0,007. Conclusion: The findings highlight that vision-related quality of life
influences the occurrence of falls in the elderly population. Emphasizing the importance of eye
health care, regular ophthalmologic examinations are essential to ensure greater autonomy and
healthier aging for older adults. Low education levels contribute to difficulties in accessing
information about eye care and fall prevention, underscoring the need for preventive and
educational strategies for the elderly.

Autism Spectrum Disorder is a multifactorial brain development disorder with a strong genetic basis, encompassing several conditions with apparently different phenotypes across three levels of support. The WHO estimates that one in every hundred children is diagnosed with ASD worldwide and that there is a higher prevalence in boys, with a ratio of 3:1 currently. Studies show that, in addition to changes in cognition, behavioral manifestations and difficulties in communication, a variety of gastrointestinal dysfunctions and symptoms such as constipation, abdominal pain, diarrhea, gas and vomiting can have a very variable prevalence in children with ASD compared to neurotypical children. Furthermore, children with ASD are five times more likely to develop eating difficulties associated with food selectivity than children without ASD. In this context, medicinal cannabis oil has been widely used as a therapeutic drug accessory in the management of autism and its comorbidities in Brazil. Its main components are the cannabinoids Δ9-tetrahydrocannabinol (Δ9-THC) and Cannabidiol (CBD). Therefore, we sought to verify the effectiveness of this product for pediatric patients aged 3 to 10 years with autism, in the city of Macapá and region - AP, with the following objectives: to characterize the nutritional profile of the studied population, monitor behavioral changes related to food, identify the presence of gastrointestinal symptoms and compare the effects of the compounds used among the age groups of the children. The method used was structured questionnaires and dietary scales applied at two different times: before the use of the oil and three to four months later. The children in the study used three types of oil, all with CBD: broad spectrum, full spectrum and isolated CBD. The results showed a sample with 77.78% of boys and 22.22% of girls, with the majority having a nutritional diagnosis of eutrophy. Few children presented gastrointestinal symptoms. Rigid behaviors, mealtime skills, and food selectivity were more influenced by the use of the oil, and children over 6 years of age had a higher average for food selectivity when compared to those under 6 years of age. Thus, research with medicinal Cannabis in the pediatric population shows itself to be a promising object of study, taking into account the positive effects on the disruptive behavior of patients with autism, the possibility of reducing conventional psychotropic drugs, and the few adverse effects reported by users.
Keywords: medical cannabis; autism spectrum disorder; food selectivity.

Introduction: Neurobiological modulation protocols using the Radio Electric
Asymmetric Conveyor (REAC) technology have been investigated for their
potential therapeutic effects on various neurological conditions. This study
evaluated the effects of this technology on patients diagnosed with Parkinson's
Disease (PD), a condition characterized by significant motor and psychological
impairments. Objective: To evaluate the effects of REAC technology protocols
on quality of life, pain, and psychological well-being in patients diagnosed with
Parkinson's Disease. Methods: This is a quasi-experimental, quantitative study
conducted with 50 patients diagnosed with PD. The study utilized the
WHOQOL-BREF questionnaire, the Depression, Anxiety, and Stress Scale
(DASS-21), the Visual Analog Scale for pain (VAS), and a sociodemographic
questionnaire. Results: Statistically significant differences (p < 0.001) were
observed in the WHOQOL-BREF domains of health satisfaction, physical,
psychological, and environmental aspects. However, the domains of general
quality of life and social relationships did not show significant differences. In the
parameters evaluated by DASS-21, there was a statistically significant reduction
in all levels of anxiety, depression, and stress (p < 0.001). Additionally, the VAS
showed a statistically significant reduction in pain levels. Conclusion: REAC
technology demonstrated positive effects on the psychological and physical
well-being of patients with Parkinson's Disease, particularly in reducing pain.
These findings highlight the therapeutic potential of REAC for managing
Parkinson's symptoms.

Keywords: Psychological Well-being; Pain Perception; Biomedical
Technology; Radio Electric Wave.

Type 2 Diabetes Mellitus (T2DM) is a chronic condition with high global prevalence, exerting
a significant impact on both public health and economic systems. It is characterized by a
metabolic dysfunction resulting from insufficient insulin secretion and/or peripheral
resistance to insulin action. Lifestyle-related factors, such as inadequate diet, physical
inactivity, and, more broadly, stress, have been associated with the development and
worsening of T2DM. The dysfunctional interaction between these factors contributes to
physiological alterations and negatively affects the quality of life of affected individuals. In
light of this, the aim of this study was to analyze the psycho-emotional aspects and their
relationship with biochemical indicators in the quality of life of individuals with type 2
diabetes (T2DM) receiving care at a Primary Health Care Unit. Participants included
individuals with a previous diagnosis of T2DM who received care at the Primary Health Unit
of the Federal University of Amapá. This is a descriptive study with a quantitative approach,
in which stress levels and quality of life were assessed using the Depression, Anxiety and
Stress Scale – 21 Items (DASS-21), the Diabetes-39 Quality of Life Questionnaire (D-39),
and the Diabetes Distress Scale (DDS-17). Biochemical parameters, including glycated
hemoglobin (HbA1c), fasting blood glucose, triglycerides, and cortisol, were also measured.
The majority of participants were female, over 60 years of age, retired, exclusively dependent
on the public health system (SUS), and presented systemic arterial hypertension as the most
frequent comorbidity. Regarding the DASS-21 results, most participants showed normal
levels of depression, anxiety, and stress. However, the D-39 scores revealed a significant
impact of T2DM on quality of life, particularly in the domains of diabetes control and
anxiety/concern about health status. The DDS-17 indicated higher levels of distress in the
domains of emotional burden and dietary regimen. As for the biochemical parameters, cortisol
levels were within normal ranges, while mean values of fasting glucose (186 mg/dL), HbA1c
(8.41%), and triglycerides (169 mg/dL) were elevated compared to reference values. Overall,
the findings reveal biochemical alterations compatible with poor glycemic control, alongside
indicators of emotional distress and impaired quality of life, reinforcing the importance of
comprehensive and interdisciplinary approaches in the clinical management of T2DM.
Keywords: Glycemic Control; Psychological Stress; Quality of Life.

Introduction: Viral hepatitis is an infection caused by different viruses that affect the
liver. The infection is usually silent, increasing the problem of early detection and
treatment. Objective: To describe the clinical, laboratory and epidemiological aspects
and factors associated with cases of hepatitis B and C treated at the Reference Center for
Tropical Diseases in the state of Amapá. Material and methods: We opted for an
exploratory, descriptive methodology with a quantitative and qualitative approach. Data
collection was carried out by searching documents, medical records, epidemiological
bulletins and others that deal with the subject, from 2013 to 2023, 254 medical records
were analyzed of hepatitis B and C patients who have treated or are still being treated, for
the qualitative study took place through the application of a semi-structured interview, in
which eight patients who accepted the terms of the research and who are being treated for
hepatitis B and hepatitis C in the reference unit of the state of Amapá were interviewed.
Quantitative data analysis was carried out using Microsoft Excel 2019 software and
Statistical Package for the Social Sciences software version 26. The variables were
subjected to the Kolmogorov-Smirnov normality test to check whether they were suitable
for parametric tests, Pearson's chi-square association test to detect associations between
responses and variables and the Content Analysis method, with the support of ATLAS.ti®
software version 25 in relation to qualitative analysis for the management of coded data.
Preliminary results: 2019 showed the highest percentage of patients starting treatment
for viral hepatitis (17.9%), followed by 2021 (14.3%) and 2017 (12.3%) (Table 1). In
addition, based on the qualitative analysis, 164 citations were identified in the textual
corpus, emotions and feelings 34 (20.73%), adversities encountered 28 (17.07%),
treatment 26 (15.85%), discovery and talk of diagnosis 21 (12.80%), professional health
guidance 16 (9.75%), viabilities encountered 16 (9.75%), family dynamics 11 (6.70%),
had no knowledge 8 (4.87%), knowledge of the disease 4 (2.43%). Initial considerations: The evidence presented leads us to conclude that care for viral hepatitis, especially B and C, is fragile when it comes to monitoring patients, both in terms of trained professionals, laboratories and diagnostic tests, as well as sociais issues and the well-being of those affected by the disease. Other associated factors, such as fear, anxietyand lack of financial resources to meet needs, are factors that have an impact on life and  the success of treatment. In view of the above, there is an urgent need to expand accessto comprehensive care for users with viral hepatitis and timely investigations to discover the disease in order to promote early treatment to avoid severe complications. It is essential that health professionals have ownership of the line of care and finally that the difficulties of decentralizing this care are overcome.

.Introduction: The COVID-19 pandemic has caused chaos in public health worldwide, also resulting in economic losses. Emergency actions have highlighted the importance of continuity of services provided by banking professionals, amid the risk of increased exposure and illness. Objective: To investigate the occurrence of COVID-19 in banking professionals in the Metropolitan Region of Macapá, in the state of Amapá. Materials and methods: This is a cross-sectional analytical study carried out at the Financial Workers' Union of Amapá (Sintraf-AP), as well as public and private banking institutions distributed throughout the MMR. A total of 96 professionals working in the banking sector were interviewed from June to August 2021. A structured questionnaire was applied on issues relevant to sociodemographic, clinical, and work characteristics, and RT-qPCR samples were subsequently collected. The information was organized in a Microsoft Excel 2019 database and then statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS) version 25.0. Quantitative variables were characterized by absolute and relative frequencies (in %) and Pearson's Chi-Square Test was performed, considering a significance level of 5% (p<0.05). This research was conducted as part of the project “Randomized COVID-19 testing: an alternative to mass testing to monitor SARS-CoV-2 infections in the population of Amapá, Brazil”. Results: the percentage of positive results, through the RT-qPCR test (1%), was similar to that of the RMM population (0.96%), however, when observing the data regarding the percentage of self-declared individuals diagnosed with COVID-19 (78.1%), up to the time of collection, it was significantly higher than that of this population (13.6%). The majority of those diagnosed with the disease were between 31 and 50 years old (66.67%), were female (50.67%), self-declared brown (62.66%), with a family income of two to five minimum wages (42.67%), residents of the municipality of Macapá (56%), with higher education (56%), lived in masonry housing (93.33%), with access to running water (58.67%) and private transportation (97.34%). There was also a low presence of family members with comorbidities living with them. The presence of symptoms common to COVID-19 among those investigated was low, not reflected in the number of diagnoses. There was a predominance of the RT-qPCR test (69.3%), of individuals who had recent contact with a person diagnosed with the disease (76%), had received at least one dose of the vaccine (92%), were not part of the risk group (85.34%) and did not live with a person in the risk group (57.34%). Regarding work activities, it is noted that the majority of those diagnosed are linked to a public institution (58.7%), work directly with the public (45.07%), have a high frequency of care (45.33%) and had a positive diagnosis while performing their duties (94.7%). The association test indicated that being at work was a risk factor for COVID-19 contamination for the participants. Final considerations: the scope of the data indicates the epidemiological scenario of COVID-19 among bank employees, and is essential in supporting public health actions and policies to combat the pandemic, especially in relation to the public investigated.